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Distinct prion-like strains of amyloid beta implicated in phenotypic diversity of Alzheimer's disease
Vast evidence on human prions demonstrates that variable disease phenotypes, rates of propagation, and targeting of distinct brain structures are determined by unique conformers (strains) of pathogenic prion protein (PrP(Sc)). Recent progress in the development of advanced biophysical tools that inv...
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| 發表在: | Prion |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Taylor & Francis
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4981201/ https://ncbi.nlm.nih.gov/pubmed/26809345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2015.1123371 |
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