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Distinct prion-like strains of amyloid beta implicated in phenotypic diversity of Alzheimer's disease
Vast evidence on human prions demonstrates that variable disease phenotypes, rates of propagation, and targeting of distinct brain structures are determined by unique conformers (strains) of pathogenic prion protein (PrP(Sc)). Recent progress in the development of advanced biophysical tools that inv...
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| Veröffentlicht in: | Prion |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4981201/ https://ncbi.nlm.nih.gov/pubmed/26809345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2015.1123371 |
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