Lipophosphoglycans from Leishmania amazonensis Strains Display Immunomodulatory Properties via TLR4 and Do Not Affect Sand Fly Infection

The immunomodulatory properties of lipophosphoglycans (LPG) from New World species of Leishmania have been assessed in Leishmania infantum and Leishmania braziliensis, the causative agents of visceral and cutaneous leishmaniasis, respectively. This glycoconjugate is highly polymorphic among species...

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Détails bibliographiques
Publié dans:PLoS Negl Trop Dis
Auteurs principaux: Nogueira, Paula M., Assis, Rafael R., Torrecilhas, Ana C., Saraiva, Elvira M., Pessoa, Natália L., Campos, Marco A., Marialva, Eric F., Ríos-Velasquez, Cláudia M., Pessoa, Felipe A., Secundino, Nágila F., Rugani, Jerônimo N., Nieves, Elsa, Turco, Salvatore J., Melo, Maria N., Soares, Rodrigo P.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980043/
https://ncbi.nlm.nih.gov/pubmed/27508930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004848
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