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Mitochondrial reactive oxygen species regulate the strength of inhibitory GABA-mediated synaptic transmission

Neuronal communication imposes a heavy metabolic burden in maintaining ionic gradients essential for action potential firing and synaptic signaling. Although cellular metabolism is known to regulate excitatory neurotransmission, it is still unclear whether the brain’s energy supply affects inhibitor...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Accardi, Michael V., Daniels, Bryan A., Brown, Patricia M.G.E., Fritschy, Jean-Marc, Tyagarajan, Shiva K., Bowie, Derek
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4977183/
https://ncbi.nlm.nih.gov/pubmed/24430741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4168
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