MtDNA analysis reveals enriched pathogenic mutations in Tibetan highlanders

Tibetan highlanders, including Tibetans, Monpas, Lhobas, Dengs and Sherpas, are considered highly adaptive to severe hypoxic environments. Mitochondrial DNA (mtDNA) might be important in hypoxia adaptation given its role in coding core subunits of oxidative phosphorylation. In this study, we employe...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kang, Longli, Zheng, Hong-Xiang, Zhang, Menghan, Yan, Shi, Li, Lei, Liu, Lijun, Liu, Kai, Hu, Kang, Chen, Feng, Ma, Lifeng, Qin, Zhendong, Wang, Yi, Wang, Xiaofeng, Jin, Li
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976311/
https://ncbi.nlm.nih.gov/pubmed/27498855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31083
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