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Excision of HIV-1 DNA by Gene Editing: A Proof-of-Concept In Vivo Study
A CRISPR/Cas9 gene editing strategy has been remarkable in excising segments of integrated HIV-1 DNA sequences from the genome of latently infected human cell lines and by introducing InDel mutations, suppressing HIV-1 replication in patient-derived CD4+ T-cells, ex vivo. Here, we employed a short v...
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| 發表在: | Gene Ther |
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| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4974122/ https://ncbi.nlm.nih.gov/pubmed/27194423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2016.41 |
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