Rapamycin Reduced Ischemic Brain Damage in Diabetic Animals Is Associated with Suppressions of mTOR and ERK1/2 Signaling

The objectives of the present study are to investigate the activation of mTOR and ERK1/2 signaling after cerebral ischemia in diabetic rats and to examine the neuroprotective effects of rapamycin. Ten minutes transient global cerebral ischemia was induced in straptozotocin-induced diabetic hyperglyc...

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Vydáno v:Int J Biol Sci
Hlavní autoři: Liu, Ping, Yang, Xiao, Hei, Changchun, Meli, Yvonne, Niu, Jianguo, Sun, Tao, Li, P. Andy
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971741/
https://ncbi.nlm.nih.gov/pubmed/27489506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.15624
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