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Neuroprotective Role of Gap Junctions in a Neuron Astrocyte Network Model

A detailed biophysical model for a neuron/astrocyte network is developed to explore mechanisms responsible for the initiation and propagation of cortical spreading depolarizations and the role of astrocytes in maintaining ion homeostasis, thereby preventing these pathological waves. Simulations of t...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biophys J
Main Authors: Huguet, Gemma, Joglekar, Anoushka, Messi, Leopold Matamba, Buckalew, Richard, Wong, Sarah, Terman, David
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968398/
https://ncbi.nlm.nih.gov/pubmed/27463146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.05.051
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