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Neuroprotective Role of Gap Junctions in a Neuron Astrocyte Network Model

A detailed biophysical model for a neuron/astrocyte network is developed to explore mechanisms responsible for the initiation and propagation of cortical spreading depolarizations and the role of astrocytes in maintaining ion homeostasis, thereby preventing these pathological waves. Simulations of t...

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Dettagli Bibliografici
Pubblicato in:Biophys J
Autori principali: Huguet, Gemma, Joglekar, Anoushka, Messi, Leopold Matamba, Buckalew, Richard, Wong, Sarah, Terman, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968398/
https://ncbi.nlm.nih.gov/pubmed/27463146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.05.051
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