FADD is a key regulator of lipid metabolism

FADD, a classical apoptotic signaling adaptor, was recently reported to have non‐apoptotic functions. Here, we report the discovery that FADD regulates lipid metabolism. PPAR‐α is a dietary lipid sensor, whose activation results in hypolipidemic effects. We show that FADD interacts with RIP140, whic...

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Vydáno v:EMBO Mol Med
Hlavní autoři: Zhuang, Hongqin, Wang, Xueshi, Zha, Daolong, Gan, Ziyi, Cai, Fangfang, Du, Pan, Yang, Yunwen, Yang, Bingya, Zhang, Xiangyu, Yao, Chun, Zhou, Yuqiang, Jiang, Chizhou, Guan, Shengwen, Zhang, Xuerui, Zhang, Jing, Jiang, Wenhui, Hu, Qingang, Hua, Zi‐Chun
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967943/
https://ncbi.nlm.nih.gov/pubmed/27357657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201505924
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