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Activation of oligodendroglial Stat3 is required for efficient remyelination

Multiple sclerosis is the most prevalent demyelinating disease of the central nervous system (CNS) and is histologically characterized by perivascular demyelination as well as neurodegeneration. While the degree of axonal damage is correlated with clinical disability, it is believed that remyelinati...

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Bibliographic Details
Published in:Neurobiol Dis
Main Authors: Steelman, Andrew J., Zhou, Yun, Koit, Hisami, Kim, SunJa, Payne, H. Ross, Lu, Q. Richard, Li, Jianrong
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962532/
https://ncbi.nlm.nih.gov/pubmed/27060559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2016.03.023
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