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[3+2]-Cycloadditions of Azomethine Imines and Ynolates

A novel [3+2]-cycloaddition between azomethine imines and lithium ynolates is described to synthesize bicyclic pyrazolidinones. These bicyclic pyrazolidinones are versatile intermediates to form β-amino acids and monocyclic pyrazolidinones. High diastereoselectivity and stereospecificity allows acce...

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Bibliographic Details
Published in:Org Lett
Main Authors: Winterton, Sarah E., Ready, Joseph M.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961353/
https://ncbi.nlm.nih.gov/pubmed/27218461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b01104
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