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The Type I Interferon Response Determines Differences in Choroid Plexus Susceptibility between Newborns and Adults in Herpes Simplex Virus Encephalitis

Newborns are significantly more susceptible to severe viral encephalitis than adults, with differences in the host response to infection implicated as a major factor. However, the specific host signaling pathways responsible for differences in susceptibility and neurologic morbidity have remained un...

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Pubblicato in:mBio
Autori principali: Wilcox, Douglas R., Folmsbee, Stephen S., Muller, William J., Longnecker, Richard
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959527/
https://ncbi.nlm.nih.gov/pubmed/27073094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00437-16
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