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Protective effect of epigallocatechin-3-gallate (EGCG) via Nrf2 pathway against oxalate-induced epithelial mesenchymal transition (EMT) of renal tubular cells

This study evaluated effect of oxalate on epithelial mesenchymal transition (EMT) and potential anti-fibrotic property of epigallocatechin-3-gallate (EGCG). MDCK renal tubular cells were incubated with 0.5 mM sodium oxalate for 24-h with/without 1-h pretreatment with 25 μM EGCG. Microscopic examinat...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kanlaya, Rattiyaporn, Khamchun, Supaporn, Kapincharanon, Chompunoot, Thongboonkerd, Visith
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958994/
https://ncbi.nlm.nih.gov/pubmed/27452398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30233
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