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Screening dietary flavonoids for the reversal of P-glycoprotein-mediated multidrug resistance in cancer

P-glycoprotein (P-gp) serves as a therapeutic target for the development of inhibitors to overcome multidrug resistance in cancer cells. Although various approaches of virtual screening procedures have been practiced so far to develop first three generations of P-gp inhibitors, their toxicity and dr...

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Bibliografske podrobnosti
izdano v:Mol Biosyst
Main Authors: Mohana, S, Ganesan, M, Agilan, B, Karthikeyan, R, Srithar, G, Beaulah Mary, R, Ananthakrishnan, D, Velmurugan, D, Rajendra Prasad, N, Ambudkar, Suresh V.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955727/
https://ncbi.nlm.nih.gov/pubmed/27216424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6mb00187d
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