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Screening dietary flavonoids for the reversal of P-glycoprotein-mediated multidrug resistance in cancer

P-glycoprotein (P-gp) serves as a therapeutic target for the development of inhibitors to overcome multidrug resistance in cancer cells. Although various approaches of virtual screening procedures have been practiced so far to develop first three generations of P-gp inhibitors, their toxicity and dr...

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Detalhes bibliográficos
Publicado no:Mol Biosyst
Main Authors: Mohana, S, Ganesan, M, Agilan, B, Karthikeyan, R, Srithar, G, Beaulah Mary, R, Ananthakrishnan, D, Velmurugan, D, Rajendra Prasad, N, Ambudkar, Suresh V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955727/
https://ncbi.nlm.nih.gov/pubmed/27216424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6mb00187d
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