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A Sensitive and Robust High-Throughput Screening Assay for Inhibitors of the Chikungunya Virus nsP1 Capping Enzyme

Chikungunya virus (CHIKV) is a mosquito-borne Alphavirus that causes severe and debilitating disease symptoms. Alarmingly, transmission rates of CHIKV have increased dramatically over the last decade resulting in 1.7 million suspected cases in the Western hemisphere alone. There are currently no ant...

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Vydáno v:PLoS One
Hlavní autoři: Bullard-Feibelman, Kristen M., Fuller, Benjamin P., Geiss, Brian J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948833/
https://ncbi.nlm.nih.gov/pubmed/27427769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158923
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