Mapping Adipose and Muscle Tissue Expression Quantitative Trait Loci in African Americans to Identify Genes for Type 2 Diabetes and Obesity

Relative to European Americans, type 2 diabetes (T2D) is more prevalent in African Americans (AAs). Genetic variation may modulate transcript abundance in insulin-responsive tissues and contribute to risk; yet published studies identifying expression quantitative trait loci (eQTLs) in African ancest...

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Pubblicato in:Hum Genet
Autori principali: Sajuthi, Satria P., Sharma, Neeraj K., Chou, Jeff W., Palmer, Nicholette D., McWilliams, David R., Beal, John, Comeau, Mary E., Ma, Lijun, Calles-Escandon, Jorge, Demons, Jamehl, Rogers, Samantha, Cherry, Kristina, Menon, Lata, Kouba, Ethel, Davis, Donna, Burris, Marcie, Byerly, Sara J., Ng, Maggie C.Y., Maruthur, Nisa M., Patel, Sanjay R., Bielak, Lawrence F., Lange, Leslie, Guo, Xiuqing, Sale, Michèle M., Chan, Kei Hang, Monda, Keri L., Chen, Gary K., Taylor, Kira, Palmer, Cameron, Edwards, Todd L, North, Kari E., Haiman, Christopher A., Bowden, Donald W., Freedman, Barry I., Langefeld, Carl D., Das, Swapan K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947558/
https://ncbi.nlm.nih.gov/pubmed/27193597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-016-1680-8
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