Mapping Adipose and Muscle Tissue Expression Quantitative Trait Loci in African Americans to Identify Genes for Type 2 Diabetes and Obesity

Relative to European Americans, type 2 diabetes (T2D) is more prevalent in African Americans (AAs). Genetic variation may modulate transcript abundance in insulin-responsive tissues and contribute to risk; yet published studies identifying expression quantitative trait loci (eQTLs) in African ancest...

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Publié dans:Hum Genet
Auteurs principaux: Sajuthi, Satria P., Sharma, Neeraj K., Chou, Jeff W., Palmer, Nicholette D., McWilliams, David R., Beal, John, Comeau, Mary E., Ma, Lijun, Calles-Escandon, Jorge, Demons, Jamehl, Rogers, Samantha, Cherry, Kristina, Menon, Lata, Kouba, Ethel, Davis, Donna, Burris, Marcie, Byerly, Sara J., Ng, Maggie C.Y., Maruthur, Nisa M., Patel, Sanjay R., Bielak, Lawrence F., Lange, Leslie, Guo, Xiuqing, Sale, Michèle M., Chan, Kei Hang, Monda, Keri L., Chen, Gary K., Taylor, Kira, Palmer, Cameron, Edwards, Todd L, North, Kari E., Haiman, Christopher A., Bowden, Donald W., Freedman, Barry I., Langefeld, Carl D., Das, Swapan K.
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947558/
https://ncbi.nlm.nih.gov/pubmed/27193597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-016-1680-8
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