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Expression, purification and biological activity assessment of romiplostim biosimilar peptibody
BACKGROUND: Romiplostim is a peptibody analogue of thrombopoietin (TPO) which regulates platelet production. This molecule consists of two main parts: Peptide sequences which like wild type TPO, mimics stimulation of TPO receptor and IgG1Fc, (Peptide + Antibody = Peptibody). This drug is used in tre...
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| 出版年: | Daru |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4940717/ https://ncbi.nlm.nih.gov/pubmed/27401785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40199-016-0156-7 |
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