IRE1α mediates PKR activation in response to Chlamydia trachomatis infection

Protein kinase RNA activated (PKR) is a crucial mediator of anti-viral responses but is reported to be activated by multiple non-viral stimuli. However, mechanisms underlying PKR activation, particularly in response to bacterial infection, remain poorly understood. We have investigated mechanisms of...

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Détails bibliographiques
Publié dans:Microbes Infect
Auteurs principaux: Webster, Steve J., Ellis, Lou, O'Brien, Louise M., Tyrrell, Beatrice, Fitzmaurice, Timothy J., Elder, Matthew J., Clare, Simon, Chee, Ronnie, Gaston, J.S. Hill, Goodall, Jane C.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2016
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936793/
https://ncbi.nlm.nih.gov/pubmed/27021640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2016.03.010
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