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Investigating Hydrophilic Pores in Model Lipid Bilayers using Molecular Simulations: Correlating Bilayer Properties with Pore Formation Thermodynamics

Cell-penetrating and antimicrobial peptides show remarkable ability to translocate across physiological membranes. Along with factors such as electric potential induced-perturbations of membrane structure and surface tension effects, experiments invoke pore-like membrane configurations during the so...

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Bibliographic Details
Published in:Langmuir
Main Authors: Hu, Yuan, Sinha, Sudipta Kumar, Patel, Sandeep
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934177/
https://ncbi.nlm.nih.gov/pubmed/25614183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/la504049q
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