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Covalent Tethering of Fragments For Covalent Probe Discovery()

Covalent probes and drugs have found widespread use as research tools and clinical agents. Covalent probes are useful because of their increased intracellular potency and because covalent labeling of cellular proteins can be tracked using click chemistry. Covalent drugs, on the other hand, can overc...

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Publicat a:Medchemcomm
Autors principals: Kathman, Stefan G., Statsyuk, Alexander V.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933313/
https://ncbi.nlm.nih.gov/pubmed/27398190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5md00518c
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