An explorative study to assess the association between health-related quality of life and the recommended phase II dose in a phase I trial: idarubicin-loaded beads for chemoembolisation of hepatocellular carcinoma

OBJECTIVES: The objective of this study was to explore the association between health-related quality of life (HRQoL) and the recommended phase 2 dose in a phase I clinical trial according to the Time to HRQoL deterioration approach (TTD). SETTING: This is a phase I dose-escalation trial of transart...

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Dettagli Bibliografici
Pubblicato in:BMJ Open
Autori principali: Anota, Amélie, Boulin, Mathieu, Dabakuyo-Yonli, Sandrine, Hillon, Patrick, Cercueil, Jean-Pierre, Minello, Anne, Jouve, Jean-Louis, Paoletti, Xavier, Bedenne, Laurent, Guiu, Boris, Bonnetain, Franck
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2016
Soggetti:
Oncology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4932346/
https://ncbi.nlm.nih.gov/pubmed/27342239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2015-010696
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