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Retinoic acid treated human dendritic cells induce T regulatory cells via the expression of CD141 and GARP which is impaired with age

Aged subjects display increased susceptibility to mucosal diseases. Retinoic Acid (RA) plays a major role in inducing tolerance in the mucosa. RA acts on Dendritic cells (DCs) to induce mucosal tolerance. Here we compared the response of DCs from aged and young individuals to RA with a view to under...

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Bibliografski detalji
Izdano u:Aging (Albany NY)
Glavni autori: Agrawal, Sudhanshu, Ganguly, Sreerupa, Tran, Alexander, Sundaram, Padmaja, Agrawal, Anshu
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931828/
https://ncbi.nlm.nih.gov/pubmed/27244900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.100973
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