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Antibacterial Drug Discovery Targeting the Lipopolysaccharide Biosynthetic Enzyme LpxC
The enzyme LpxC (UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase) is broadly conserved across Gram-negative bacteria and is essential for synthesis of lipid A, the membrane anchor of the lipopolysaccharides (LPSs), which are a major component of the outer membrane in nearly all Gram-n...
保存先:
| 出版年: | Cold Spring Harb Perspect Med |
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| 第一著者: | |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cold Spring Harbor Laboratory Press
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4930914/ https://ncbi.nlm.nih.gov/pubmed/27235477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a025304 |
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