Brain structure, cognition and negative symptoms in schizophrenia are associated with serum levels of polysialic acid-modified NCAM

The neural cell adhesion molecule (NCAM) is a glycoprotein implicated in cell–cell adhesion, neurite outgrowth and synaptic plasticity. Polysialic acid (polySia) is mainly attached to NCAM (polySia-NCAM) and has an essential role in regulating NCAM-dependent developmental processes that require plas...

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Publicat a:Transl Psychiatry
Autors principals: Piras, F, Schiff, M, Chiapponi, C, Bossù, P, Mühlenhoff, M, Caltagirone, C, Gerardy-Schahn, R, Hildebrandt, H, Spalletta, G
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930132/
https://ncbi.nlm.nih.gov/pubmed/26460482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2015.156
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