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Distribution of MEFV gene mutations and R202Q polymorphism in the Serbian population and their influence on oxidative stress and clinical manifestations of inflammation

BACKGROUND: The Mediterranean fever (MEFV) gene codes for protein pyrin, one of the regulators of inflammasome activity in innate immune cells. Mutations in this gene are considered the primary cause of Familial Mediterranean fever, but are also found in other monogenic and multifactorial autoinflam...

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Bibliografski detalji
Izdano u:Pediatr Rheumatol Online J
Glavni autori: Milenković, Jelena, Vojinović, Jelena, Debeljak, Maruša, Toplak, Nataša, Lazarević, Dragana, Avčin, Tadej, Jevtović-Stoimenov, Tatjana, Pavlović, Dušica, Bojanić, Vladmila, Milojković, Maja, Kocić, Gordana, Veljković, Andrej
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929733/
https://ncbi.nlm.nih.gov/pubmed/27364639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12969-016-0097-1
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