Distribution of MEFV gene mutations and R202Q polymorphism in the Serbian population and their influence on oxidative stress and clinical manifestations of inflammation

BACKGROUND: The Mediterranean fever (MEFV) gene codes for protein pyrin, one of the regulators of inflammasome activity in innate immune cells. Mutations in this gene are considered the primary cause of Familial Mediterranean fever, but are also found in other monogenic and multifactorial autoinflam...

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Bibliographic Details
Published in:Pediatr Rheumatol Online J
Main Authors: Milenković, Jelena, Vojinović, Jelena, Debeljak, Maruša, Toplak, Nataša, Lazarević, Dragana, Avčin, Tadej, Jevtović-Stoimenov, Tatjana, Pavlović, Dušica, Bojanić, Vladmila, Milojković, Maja, Kocić, Gordana, Veljković, Andrej
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929733/
https://ncbi.nlm.nih.gov/pubmed/27364639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12969-016-0097-1
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