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DADA2: High resolution sample inference from Illumina amplicon data
We present DADA2, a software package that models and corrects Illumina-sequenced amplicon errors. DADA2 infers sample sequences exactly, without coarse-graining into OTUs, and resolves differences of as little as one nucleotide. In several mock communities DADA2 identified more real variants and out...
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Veröffentlicht in: | Nat Methods |
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Hauptverfasser: | , , , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2016
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4927377/ https://ncbi.nlm.nih.gov/pubmed/27214047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3869 |
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