Prolonged Culture of Aligned Skeletal Myotubes on Micromolded Gelatin Hydrogels

In vitro models of skeletal muscle are critically needed to elucidate disease mechanisms, identify therapeutic targets, and test drugs pre-clinically. However, culturing skeletal muscle has been challenging due to myotube delamination from synthetic culture substrates approximately one week after in...

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Pubblicato in:Sci Rep
Autori principali: Bettadapur, Archana, Suh, Gio C., Geisse, Nicholas A., Wang, Evelyn R., Hua, Clara, Huber, Holly A., Viscio, Alyssa A., Kim, Joon Young, Strickland, Julie B., McCain, Megan L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924097/
https://ncbi.nlm.nih.gov/pubmed/27350122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28855
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