Nuclear PKC-θ facilitates rapid transcriptional responses in human memory CD4(+) T cells through p65 and H2B phosphorylation

Memory T cells are characterized by their rapid transcriptional programs upon re-stimulation. This transcriptional memory response is facilitated by permissive chromatin, but exactly how the permissive epigenetic landscape in memory T cells integrates incoming stimulatory signals remains poorly unde...

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Détails bibliographiques
Publié dans:J Cell Sci
Auteurs principaux: Li, Jasmine, Hardy, Kristine, Phetsouphanh, Chan, Tu, Wen Juan, Sutcliffe, Elissa L., McCuaig, Robert, Sutton, Christopher R., Zafar, Anjum, Munier, C. Mee Ling, Zaunders, John J., Xu, Yin, Theodoratos, Angelo, Tan, Abel, Lim, Pek Siew, Knaute, Tobias, Masch, Antonia, Zerweck, Johannes, Brezar, Vedran, Milburn, Peter J., Dunn, Jenny, Casarotto, Marco G., Turner, Stephen J., Seddiki, Nabila, Kelleher, Anthony D., Rao, Sudha
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920249/
https://ncbi.nlm.nih.gov/pubmed/27149922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.181248
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