Nuclear PKC-θ facilitates rapid transcriptional responses in human memory CD4(+) T cells through p65 and H2B phosphorylation

Memory T cells are characterized by their rapid transcriptional programs upon re-stimulation. This transcriptional memory response is facilitated by permissive chromatin, but exactly how the permissive epigenetic landscape in memory T cells integrates incoming stimulatory signals remains poorly unde...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Cell Sci
Main Authors: Li, Jasmine, Hardy, Kristine, Phetsouphanh, Chan, Tu, Wen Juan, Sutcliffe, Elissa L., McCuaig, Robert, Sutton, Christopher R., Zafar, Anjum, Munier, C. Mee Ling, Zaunders, John J., Xu, Yin, Theodoratos, Angelo, Tan, Abel, Lim, Pek Siew, Knaute, Tobias, Masch, Antonia, Zerweck, Johannes, Brezar, Vedran, Milburn, Peter J., Dunn, Jenny, Casarotto, Marco G., Turner, Stephen J., Seddiki, Nabila, Kelleher, Anthony D., Rao, Sudha
פורמט: Artigo
שפה:Inglês
יצא לאור: The Company of Biologists Ltd 2016
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920249/
https://ncbi.nlm.nih.gov/pubmed/27149922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.181248
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