Delamination of neural crest cells requires transient and reversible Wnt inhibition mediated by Dact1/2

Delamination of neural crest (NC) cells is a bona fide physiological model of epithelial-to-mesenchymal transition (EMT), a process that is influenced by Wnt/β-catenin signalling. Using two in vivo models, we show that Wnt/β-catenin signalling is transiently inhibited at the time of NC delamination....

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Udgivet i:Development
Main Authors: Rabadán, M. Angeles, Herrera, Antonio, Fanlo, Lucia, Usieto, Susana, Carmona-Fontaine, Carlos, Barriga, Elias H., Mayor, Roberto, Pons, Sebastián, Martí, Elisa
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920176/
https://ncbi.nlm.nih.gov/pubmed/27122165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.134981
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