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“Reverse Genomics” Predicts Function of Human Conserved Noncoding Elements

Evolutionary changes in cis-regulatory elements are thought to play a key role in morphological and physiological diversity across animals. Many conserved noncoding elements (CNEs) function as cis-regulatory elements, controlling gene expression levels in different biological contexts. However, dete...

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Bibliographic Details
Published in:Mol Biol Evol
Main Authors: Marcovitz, Amir, Jia, Robin, Bejerano, Gill
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909134/
https://ncbi.nlm.nih.gov/pubmed/26744417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msw001
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