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Autophagy induction targeting mTORC1 enhances Mycobacterium tuberculosis replication in HIV co-infected human macrophages

To survive and replicate in macrophages Mycobacterium tuberculosis (Mtb) has developed strategies to subvert host defence mechanisms, including autophagy. Autophagy induction has the potential to clear Mtb, but little is known about its effect during controlled tuberculosis and HIV co-infection. Mam...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Andersson, Anna-Maria, Andersson, Blanka, Lorell, Christoffer, Raffetseder, Johanna, Larsson, Marie, Blomgran, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908603/
https://ncbi.nlm.nih.gov/pubmed/27302320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28171
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