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Synthesis, Formulation, and Adjuvanticity of Monodesmosidic Saponins with Olenanolic Acid, Hederagenin and Gypsogenin Aglycones, and some C‐28 Ester Derivatives
In an attempt to discover a new synthetic vaccine adjuvant, the glycosylation of hederagenin, gypsogenin, and oleanolic acid acceptors with di‐ and trisaccharide donors to generate a range of mimics of natural product QS‐21 was carried out. The saponins were formulated with phosphatidylcholine and c...
Tallennettuna:
Julkaisussa: | ChemistryOpen |
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Päätekijät: | , , , , , , |
Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
John Wiley and Sons Inc.
2015
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4906508/ https://ncbi.nlm.nih.gov/pubmed/27308200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201500149 |
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