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Frequency of CD4+CD25+Foxp3+ cells in peripheral blood in relation to urinary bladder cancer malignancy indicators before and after surgical removal

Tumor cells communicate with stromal cells, including cancer-associated fibroblasts (CAFs) and tumor-associated macrophages (TAMs), to form microenvironment inhibiting immune responses. Regulatory T cells (Tregs, CD4+CD25+FoxP3+) stimulate immune tolerance and facilitate tumor progression. We analyz...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Jóźwicki, Wojciech, Brożyna, Anna A., Siekiera, Jerzy, Slominski, Andrzej T.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905485/
https://ncbi.nlm.nih.gov/pubmed/26862849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7199
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