Mechanisms of PDGF siRNA-mediated inhibition of bone cancer pain in the spinal cord

Patients with tumors that metastasize to bone frequently suffer from debilitating pain, and effective therapies for treating bone cancer are lacking. This study employed a novel strategy in which herpes simplex virus (HSV) carrying a small interfering RNA (siRNA) targeting platelet-derived growth fa...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Xu, Yang, Liu, Jia, He, Mu, Liu, Ran, Belegu, Visar, Dai, Ping, Liu, Wei, Wang, Wei, Xia, Qing-Jie, Shang, Fei-Fei, Luo, Chao-Zhi, Zhou, Xue, Liu, Su, McDonald, JohnW., Liu, Jin, Zuo, Yun-Xia, Liu, Fei, Wang, Ting-Hua
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4901320/
https://ncbi.nlm.nih.gov/pubmed/27282805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27512
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