Allosteric modulation in monomers and oligomers of a G protein-coupled receptor

The M(2) muscarinic receptor is the prototypic model of allostery in GPCRs, yet the molecular and the supramolecular determinants of such effects are unknown. Monomers and oligomers of the M(2) muscarinic receptor therefore have been compared to identify those allosteric properties that are gained i...

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Bibliografiska uppgifter
I publikationen:eLife
Huvudupphovsmän: Shivnaraine, Rabindra V, Kelly, Brendan, Sankar, Krishana S, Redka, Dar'ya S, Han, Yi Rang, Huang, Fei, Elmslie, Gwendolynne, Pinto, Daniel, Li, Yuchong, Rocheleau, Jonathan V, Gradinaru, Claudiu C, Ellis, John, Wells, James W
Materialtyp: Artigo
Språk:Inglês
Publicerad: eLife Sciences Publications, Ltd 2016
Ämnen:
Biochemistry
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900804/
https://ncbi.nlm.nih.gov/pubmed/27151542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.11685
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