Insights into Length-Dependent Regulation of Cardiac Cross-Bridge Cycling kinetics in Human Myocardium

Cross-bridge cycling kinetics play an essential role in the heart’s ability to contract and relax. The rate of tension redevelopment (k(tr)) slows down as a muscle length is increased in intact human myocardium. We set out to determine the effect of rapid length step changes and protein kinase A (PK...

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Publicado en:Arch Biochem Biophys
Autores principales: Milani-Nejad, Nima, Chung, Jae-Hoon, Canan, Benjamin D., Davis, Jonathan P., Fedorov, Vadim V., Higgins, Robert S.D., Kilic, Ahmet, Mohler, Peter J., Janssen, Paul M.L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899103/
https://ncbi.nlm.nih.gov/pubmed/26854725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2016.02.005
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