Wird geladen...
G2385R and I2020T Mutations Increase LRRK2 GTPase Activity
The LRRK2 mutation is a major causal mutation in familial Parkinson's disease. Although LRRK2 contains functional GTPase and kinase domains and their activities are altered by pathogenic mutations, most studies focused on LRRK2 kinase activity because the most prevalent mutant, G2019S, enhances...
Gespeichert in:
| Veröffentlicht in: | Biomed Res Int |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Hindawi Publishing Corporation
2016
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4897664/ https://ncbi.nlm.nih.gov/pubmed/27314038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7917128 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|