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Roles of paxillin family members in adhesion and ECM degradation coupling at invadosomes

Invadosomes are acto-adhesive structures able to both bind the extracellular matrix (ECM) and digest it. Paxillin family members—paxillin, Hic-5, and leupaxin—are implicated in mechanosensing and turnover of adhesion sites, but the contribution of each paxillin family protein to invadosome activitie...

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Biol
Hauptverfasser: Petropoulos, Christos, Oddou, Christiane, Emadali, Anouk, Hiriart-Bryant, Edwige, Boyault, Cyril, Faurobert, Eva, Vande Pol, Scott, Kim-Kaneyama, Joo-ri, Kraut, Alexandra, Coute, Yohann, Block, Marc, Albiges-Rizo, Corinne, Destaing, Olivier
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896053/
https://ncbi.nlm.nih.gov/pubmed/27269065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201510036
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