Cationic Gadolinium Chelate for Magnetic Resonance Imaging of Cartilaginous Defects

The ability to detect meniscus defects by magnetic resonance arthrography (MRA) can be highly variable. To improve the delineation of fine tears, we synthesized a cationic gadolinium complex, (Gd-DOTA-AM(4))(2+), that can electrostatically interact with Glycosaminoglycans (GAGs). The complex has a l...

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Bibliographic Details
Published in:Contrast Media Mol Imaging
Main Authors: Nwe, Kido, Huang, Ching-Hui, Qu, Feini, Warden-Rothman, Robert, Zhang, Clare Y., Mauck, Robert L., Tsourkas, Andrew
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892988/
https://ncbi.nlm.nih.gov/pubmed/26853708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmmi.1685
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