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The hormone response element mimic sequence of GAS5 lncRNA is sufficient to induce apoptosis in breast cancer cells
Growth arrest-specific 5 (GAS5) lncRNA promotes apoptosis, and its expression is down-regulated in breast cancer. GAS5 lncRNA is a decoy of glucocorticoid/related receptors; a stem-loop sequence constitutes the GAS5 hormone response element mimic (HREM), which is essential for the regulation of brea...
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| Publié dans: | Oncotarget |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Impact Journals LLC
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4891107/ https://ncbi.nlm.nih.gov/pubmed/26862727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7173 |
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