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Dabrafenib in an elderly patient with metastatic melanoma and BRAF V600R mutation: a case report
BACKGROUND: Approximately 50 % of malignant melanomas harbor activating point mutations in the BRAF gene. Typically, these mutations result in the substitution of the amino acid valine at codon 600 of the gene, and 90–95 % of mutations are either BRAF(V600E) or BRAF(V600K). Specific BRAF inhibitors...
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| 出版年: | J Med Case Rep |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4890269/ https://ncbi.nlm.nih.gov/pubmed/27255157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13256-016-0953-0 |
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