ROR1 is essential for proper innervation of auditory hair cells and hearing in humans and mice

Hair cells of the inner ear, the mechanosensory receptors, convert sound waves into neural signals that are passed to the brain via the auditory nerve. Little is known about the molecular mechanisms that govern the development of hair cell–neuronal connections. We ascertained a family with autosomal...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Diaz-Horta, Oscar, Abad, Clemer, Sennaroglu, Levent, Foster, Joseph, DeSmidt, Alexandra, Bademci, Guney, Tokgoz-Yilmaz, Suna, Duman, Duygu, Cengiz, F. Basak, Grati, M’hamed, Fitoz, Suat, Liu, Xue Z., Farooq, Amjad, Imtiaz, Faiqa, Currall, Benjamin B., Morton, Cynthia Casson, Nishita, Michiru, Minami, Yasuhiro, Lu, Zhongmin, Walz, Katherina, Tekin, Mustafa
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889368/
https://ncbi.nlm.nih.gov/pubmed/27162350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522512113
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