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A Low-Copy-Number Plasmid for Retrieval of Toxic Genes from BACs and Generation of Conditional Targeting Constructs

Bacterial Artificial Chromosome (BAC) clones are widely used for retrieving genomic DNA sequences for gene targeting. In this study, low-copy-number plasmids pBAC-FB, pBAC-FC, and pBAC-DE, which carry the F plasmid replicon, were generated from pBACe3.6. pBAC-FB was successfully used to retrieve a s...

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Detalhes bibliográficos
Publicado no:Mol Biotechnol
Main Authors: Na, Giyoun, Wolfe, Andrew, Ko, CheMyong, Youn, Hyesook, Lee, Young-Min, Byun, Sung June, Jeon, Iksoo, Koo, Yongbum
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888602/
https://ncbi.nlm.nih.gov/pubmed/22945876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12033-012-9591-y
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