Antibody mediated therapy targeting CD47 inhibits tumor progression of hepatocellular carcinoma

Human hepatocellular carcinoma (HCC) has a high rate of tumor recurrence and metastasis, resulting in shortened survival times. The efficacy of current systemic therapies for HCC is limited. In this study, we used xenograft tumor models to investigate the use of antibodies that block CD47 and inhibi...

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Vydáno v:Cancer Lett
Hlavní autoři: Xiao, Zhenyu, Chung, Haniee, Banan, Babak, Manning, Pamela T., Ott, Katherine C., Lin, Shin, Capoccia, Benjamin J., Subramanian, Vijay, Hiebsch, Ronald R., Upadhya, Gundumi A., Mohanakumar, Thalachallour, Frazier, William A., Lin, Yiing, Chapman, William C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886734/
https://ncbi.nlm.nih.gov/pubmed/25721088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.02.036
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