The pharmacokinetics of dexmedetomidine during long-term infusion in critically ill pediatric patients. A Bayesian approach with informative priors

The purpose of this study was to assess the pharmacokinetics of dexmedetomidine in the ICU settings during the prolonged infusion and to compare it with the existing literature data using the Bayesian population modeling with literature-based informative priors. Thirty-eight patients were included i...

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Veröffentlicht in:J Pharmacokinet Pharmacodyn
Hauptverfasser: Wiczling, Paweł, Bartkowska-Śniatkowska, Alicja, Szerkus, Oliwia, Siluk, Danuta, Rosada-Kurasińska, Jowita, Warzybok, Justyna, Borsuk, Agnieszka, Kaliszan, Roman, Grześkowiak, Edmund, Bienert, Agnieszka
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2016
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886153/
https://ncbi.nlm.nih.gov/pubmed/27221375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-016-9474-0
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